Whiteboard Update: Transforming the Diagnosis and Treatment of Chronic Lymphocytic Leukemia


Released On
June 29, 2018

Expires On
June 29, 2019

Media Type

Completion Time
15 minutes

Hematology/Oncology, Oncology

Chronic Lymphocytic Leukemia

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This activity is provided by Imedex®, LLC.


Supported by educational grants from Pharmacyclics, an AbbVie Company and Janssen Biotech, Inc. and TG Therapeutics.

Credit Available

  • Physicians — maximum of 0.25 AMA PRA Category 1 Credit

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

This educational activity is designed for US-based hematologists, medical oncologists, hematopathologists, other healthcare professionals interested in the therapeutic management of hematologic malignancies.

Program Overview

Dramatic progress has been made in our understanding of the clinical, biological and molecular heterogeneity of chronic lymphocytic leukemia (CLL). Despite this, treatment challenges remain, particularly in patients with high-risk disease. This Whiteboard Update helps address the question of how to best integrate the latest knowledge into clinical practice to help guide treatment choices for patients with high-risk CLL. Topics of discussion include examinations of the mechanisms of action of BCR signaling inhibitors, anti-CD20 agents, and anti-apoptotic BCL2 inhibitors.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Analyze the clinical trial data regarding response rates, risks, and benefits for new and emerging agents for CLL
  • Develop individualized treatment plans for patients with CLL incorporating new agents based on genetic and molecular abnormalities, benefits and risks, comorbidities, and patient profiles



John N. Allan, MD

Weill Cornell Medicine
New York, New York

Physician Accreditation Statement

Imedex, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physician Credit Designation

Imedex, LLC designates this internet-based enduring educational activity for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), Imedex, LLC must ensure balance, objectivity, independence, and scientific rigor in its educational activities. Faculty are instructed to provide a balanced view of therapeutic options by utilizing generic names to ensure impartiality.

All faculty participating in an Imedex activity are required to disclose relevant financial relationships that may be considered to be related to the subject matter of the educational activity. Disclosure of these commitments and/or relationships is included in these course materials so that participants in the activity may formulate their own judgments in interpreting its content and evaluating its recommendations.

The following indicates the faculty disclosure declaration information and the nature of those commercial relationships.

John N. Allan, MD

  • Consultant: AbbVie; Genentech; KLJ Associates; Sunesis; Verastem

Disclosure of Unlabeled Use

This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the US Food and Drug Administration (FDA) and/or other national regulatory agencies in the United States and other countries. Participants in the United States are encouraged to consult the FDA-approved product labeling for any drug or device mentioned in this program before use. Participants from other countries should consult with their respective regulatory authorities.

The opinions expressed in this webcast are the opinions of the authors and do not necessarily reflect the opinions of Imedex.

Instructions for Participation and Credit

AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 0.5 hour of Category 1 credit for completing this program.

In order to receive credit, participants must successfully complete the post-test by scoring a grade of 75% or higher in three attempts or less and complete the online evaluation form. You will receive an online CME statement of credit to print for your records.

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above.


The material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual’s own physician.

About Imedex

Imedex is a brand and assumed name used by Imedex, LLC (hereby referred to as Imedex). Imedex is solely responsible for this agenda’s content. Although Imedex attempts to ensure that the information in our program is accurate and timely, matters and opinions discussed and/or presented with respect to clinical matters are those of the discussion participants only, and not necessarily those of Imedex. Moreover, although Imedex attempts to identify and integrate the most qualified medical professionals in our program, TO THE FULLEST EXTENT PERMITTED BY LAW, IMEDEX EXPRESSLY DISCLAIM ALL WARRANTIES, EITHER EXPRESS OR IMPLIED, STATUTORY OR OTHERWISE, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OF MERCHANTABILITY, NON-INFRINGEMENT OF THIRD PARTIES’ RIGHTS, AND FITNESS FOR A PARTICULAR PURPOSE, WITH RESPECT TO THE CONTENT PRESENTED. IMEDEX FURTHER MAKES NO REPRESENTATIONS OR WARRANTIES ABOUT THE ACCURACY, RELIABILITY, COMPLETENESS OR TIMELINESS OF THE CONTENT OR ANY MATERIAL PRESENTED.

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