Treatment of Relapsed/Refractory Ph+ ALL

Released On
July 13, 2022

Expires On
July 12, 2023

Media Type

Completion Time
30 minutes


Leukemia, Lymphoma, Oncology

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This activity is jointly provided by The France Foundation and the American Society for Transplantation and Cellular Therapy.

This activity is supported by an educational grant from Pfizer.

Credit Available

  • Physicians — maximum of 0.5 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

The target audience for this initiative includes hematology/oncology physicians and other members of the multidisciplinary cancer care team involved in the management of patients with acute lymphocytic leukemia.

Program Overview

This activity is the second in a series of four educational activities focusing on the treatment of relapsed/refractory ALL. Dr. Jessica Leonard, from Oregon Health and Science University, discusses diagnosis and treatment options, and will walk through a case study of a patient with Ph+ ALL.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Identify patients who could benefit from CD22-directed ADC therapy using current practice guideline recommendations
  • Develop strategies to prevent, monitor, and manage VOD associated with CD22-directed ADC therapy



Jessica Leonard, MD

Assistant Professor of Medicine
Division of Hematology/Medical Oncology
Oregon Health & Science University
Knight Cancer Institute
Portland, OR

Nurse Planner

Kirsten Roblee, MHI, BSN, RN, OCN

Administrative Nurse Manager, Oncology Infusion Services
Dublin Methodist Hospital & Grady Memorial Hospital
Ohio Health
Columbus, OH

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The France Foundation (TFF) and the American Society for Transplantation and Cellular Therapy. TFF is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

The France Foundation designates this enduring activity for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Disclosures of Conflicts of Interest

Staff/Content Reviewers

Erika Fox has no financial relationships to disclose.
Heather Tarbox, MPH has no financial relationships to disclose.
Heidi Thompson, PhD has no financial relationships to disclose.
Kirsten Kozub has no financial relationships to disclose.
Kirsten Roblee, MHI, BSN, RN, OCN has no financial relationships to disclose.

Planning Committee

Jessica Leonard, MD has no financial relationships to disclose.

Instructions for Participation and Credit

Technical Requirements:

  1. There are no fees for participating in and receiving credit for this activity
  2. Review the activity objectives and CME/CE information
  3. Complete the CME/CE activity
  4. Complete the online posttest. A score of at least 70% is required to successfully complete this activity. The participant may take the test until successfully passed.
  5. Complete the CME/CE evaluation/attestation form. This form provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  6. Credit documentation/reporting:
    • • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

The France Foundation (TFF) and the American Society for Transplantation and Cellular Therapy (ASTCT) require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling.

This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF and ASTCT do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.


The France Foundation (TFF) and the American Society for Transplantation and Cellular Therapy (ASTCT) present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. TFF, ASTCT, and the commercial supporter(s) assume no liability for the information herein.

Contact Information

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or