A New Era in Relieving the Burden and Improving Health Outcomes of Children with Growth Hormone Deficiency

Released On
March 18, 2022

Expires On
March 18, 2023

Media Type

Completion Time
90 minutes

Endocrinology, Genetics, Pediatrics

Growth Hormones, Pediatrics

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This activity is provided by Annenberg Center for Health Sciences at Eisenhower.


Supported by an education grant from Novo Nordisk Inc.

Credit Available

  • Physicians — maximum of 1.5 AMA PRA Category 1 Credit(s)
  • Nurses — 1.5 contact hours

All other healthcare professionals completing this course will be issued a statement of participation.

Target Audience

This activity was developed for pediatric endocrinologists, pediatricians, nurse practitioners, physician assistants and other healthcare providers who treat children and adolescents with growth and growth hormone disorders.

Program Overview

Growth hormone deficiency (GHD) specialists Sara DiVall, MD, and Kevin Yuen, MD, explore ways to optimize outcomes in the diagnosis and treatment of GHD in children, including considerations for the use of long-acting growth hormone (LAGH) products. Topics include the epidemiology, clinical manifestations, and burden of GHD in children and adolescents, evidence-based diagnosis of GHD, guidelines and recommendations for treatment, integrating shared decision-making with patients and/or their parents to develop and modify the treatment plan, and clinical trial data regarding daily and new and emerging LAGH products. Case studies based on common clinical scenarios are discussed to examine how to apply this information in clinical practice to optimize long-term self-management.

Content Areas

  • Epidemiology
  • Burden of GHD
  • Shared Decision-Making
  • Somatropin Products
  • New/Emerging Long-acting Growth Hormone Products

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Implement key treatment recommendations for children and adolescents with growth hormone deficiency (competence)
  • Implement shared decision-making to help children and adolescents and their parents select a growth hormone product based on patient characteristics and needs and product labeling (competence)
  • Initiate, titrate, and monitor growth hormone therapy in children and adolescents based on patient response and tolerability (competence)
  • Describe the safety and efficacy of emerging long-acting recombinant humangrowth hormone therapies and their potential use in children and adolescents (knowledge)


Sara DiVall, MD

Associate Professor of Pediatrics
Fellowship Director
Seattle Children’s Hospital
Seattle, Washington

Kevin Yuen, MD

Medical Director
Barrow Pituitary Center
Barrow Neuroendocrine Clinic
Phoenix, Arizona

Physician Accreditation Statement

The Annenberg Center for Health Sciences at Eisenhower is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physician Credit Designation

The Annenberg Center for Health Sciences at Eisenhower designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Accreditation Statement

Annenberg Center for Health Sciences is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

Nursing Credit Designation

A maximum of 1.5 contact hours may be earned for successful completion of this activity.

Disclosures of Conflicts of Interest

It is the policy of the Annenberg Center for Health Sciences to ensure fair balance, independence, objectivity, and scientific rigor in all programming. All individuals with the potential to impact the content of an accredited education activity are expected to identify and reference off-label product use and disclose relationships with ACCME-defined ineligible companies.

The Annenberg Center for Health Sciences assesses relevant relationships with its instructors, planners, managers, and other individuals who are in a position to control the content of CE/CME activities. All relevant relationships that are identified are thoroughly vetted by the Annenberg Center for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. The Annenberg Center is committed to providing its learners with high-quality CE/CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

In accordance with the Accreditation Council for Continuing Medical Education Standards, parallel documents from other accrediting bodies, and Annenberg Center for Health Sciences policy, the following disclosures have been made:

Kevin Yuen, MD

  • Advisory Board: Chiasma, Crinetics, Ipsen, Novartis, Sandoz, Strongbridge
  • Research Support: Amryt, Ascendis, Corcept, Novartis
  • Speakers Bureau: Corcept, Novo Nordisk, Recordati

Sara DiVall, MD, has no relevant financial relationships to disclose.

The faculty for this activity has disclosed that there will be discussion about the use of products for non-FDA approved applications.

Additional content planners
The following have no significant relationship to disclose:
Lynne Schneider (medical writer)
Eugene Cullen, MD (peer reviewer)

Annenberg Center for Health Sciences
All staff at the AnnenbergCenter for Health Sciences at Eisenhower have no relevant commercial relationships to disclose.

All of the relevant financial relationships listed for these individuals have been mitigated.

Instructions for Participation and Credit

This activity is an online enduring material. Successful completion is achieved by reading and/or viewing the materials, reflecting on its implications in your practice, and completing the assessment component.

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

The faculty for this activity has disclosed that there will be discussion about the use of products for non-FDA approved applications.


The ideas and opinions presented in this educational activity are those of the faculty and do not necessarily reflect the views of the Annenberg Center and/or its agents. As in all educational activities, we encourage practitioners to use their own judgment in treating and addressing the needs of each individual patient, taking into account that patient’s unique clinical situation. The Annenberg Center disclaims all liability and cannot be held responsible for any problems that may arise from participating in this activity or following treatment recommendations presented.

Contact Information

For help or questions about this activity please contact Continuing Education: