Neuromyelitis Optica Spectrum Disorder: Improving Outcomes by Optimizing Choice of Therapy

Released On
March 29, 2022

Expires On
March 29, 2023

Media Type

Completion Time
45 minutes

Ophthalmology, Neurology

Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, NMOSD

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This continuing medical education activity is provided by Vindico Medical Education.

This activity is supported by an educational grant from Horizon Therapeutics USA, Inc.

Credit Available

  • Physicians — maximum of 0.75 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

The intended audience for this activity is neurologists, neuro-ophthalmologists, ophthalmologists, neurology nurse practitioners, neurology physician assistants, and other health care professionals involved in the management of patients with neuromyelitis optica spectrum disorder (NMOSD).

Program Overview

Neuromyelitis optica spectrum disorder is a rare autoimmune disease of the central nervous system, mainly manifesting through recurrent attacks of optic neuritis and longitudinally extensive transverse myelitis. Early stages of NMOSD are frequently misdiagnosed. The application of newer diagnostic criteria may facilitate earlier and more accurate diagnosis by assisting clinicians in identifying NMOSD in individuals who might have otherwise been diagnosed with other diseases. Treatment options have been limited until recently. Monoclonal antibodies have been used for patients with autoimmune disorders for several years, and their efficacy and safety in patients with NMOSD have been demonstrated. In this continuing education activity, expert clinicians review the latest updates on diagnosing and treating NMOSD.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Assess modalities that facilitate the early diagnosis of NMOSD.
  • Examine current NMOSD therapies based on their mechanisms of action, dosing frequency, and modes of administration.
  • Evaluate the latest clinical evidence for NMOSD treatments, including multidisciplinary approaches to NMOSD patient care.

Activity Chair

Patricia K. Coyle, MD, FAAN, FANA

Professor and Vice Chair (Clinical Affairs)
Department of Neurology
Multiple Sclerosis Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, NY


Bruce A. C. Cree, MD, PhD, MAS, FAAN, FANA

George A. Zimmermann Endowed Professor in Multiple Sclerosis
Professor of Clinical Neurology
Clinical Research Director
UCSF Weill Institute for Neurosciences
Department of Neurology
University of California San Francisco
San Francisco, CA

Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND

Distinguished Teaching Professor
Vice Chair for Clinical and Translational Research
Department of Neurology
Director, Perot Foundation Neurosciences Translational Research Center
O’Donnell Brain Institute
University of Texas Southwestern
Dallas, TX

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity

Nurse practitioners can apply for AMA PRA Category 1 Credit(s)™ through the American Academy of Nurse Practitioners Certification Board (AANPCB). AANPCB will accept AMA PRA Category 1 Credit(s)™ from organizations accredited by ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 0.75 hours credit for completing this program.

Disclosures of Conflicts of Interest

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Patricia K. Coyle, MD, FAAN, FANA
  • Consultant: Horizon
  • Independent Research Contractor: Genentech/Roche
Bruce A. C. Cree, MD, PhD, MAS, FAAN, FANA
  • Consultant: Alexion, Horizon
  • Independent Research Contractor: Genentech/Roche
Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND
  • Consultant: Alexion, Genentech/Roche, Horizon

Instructions for Participation and Credit

There are no fees for participating and receiving CME credit for this enduring activity.

To participate in this CME activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 2 of the 3 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.


This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2022 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

Contact Information

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