Prurigo Nodularis: A Caucasian Adult Male With History of Uncontrolled PN and Associated Comorbidities

Released On
January 25, 2022

Expires On
January 25, 2023

Media Type

Completion Time
15 minutes

Dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care pharmacists.

Dermatology; pruritus; lesions; nodules; quality of life; angioedema; hives; off-label agents; wheals; skin; skin of color; differential diagnosis; prurigo nodularis

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This educational activity is jointly provided by Global Education Group and Spire Learning.

This activity is supported by educational grants from Sanofi Genzyme and Regeneron Pharmaceuticals.

Credit Available

  • Physicians — maximum of 0.25 AMA PRA Category 1 Credit(s)
  • Nurses — 0.25 Contact Hours

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

The target audience will be comprised of dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care pharmacists.

Program Overview

Prurigo nodularis (PN) is a chronic condition mediated by immune and neural dysregulation and presenting with highly pruritic, hyperkeratotic papules or nodules; the condition disproportionately affects African American patients compared to the general population. There are currently no FDA-approved therapies for the treatment of PN, leading to a high level of variability in clinical practice and the use of off-label agents; the current treatment landscape, or lack thereof, highlights the need for a multimodal approach to therapy and consideration of emerging agents. As a result, many health care professionals may be unaware of the standard, off-label treatments used, as well as the clinical data surrounding promising emerging agents for PN management and as a result, may miss opportunities to deliver evidence-based care. Join our expert faculty as they discuss patient scenarios utilizing methods to avoid missed opportunities for the care team, assess the clinical efficacy and safety of standard off-label, as well as emerging therapies, and ultimately devise effective treatment plans that encourage long-term adherence and address residual disease burden for patients with PN.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • ANALYZE clinical data surrounding emerging treatments for PN.
  • ASSESS the efficacy of standard, off-label treatments currently used for PN and residual burden of disease on patients
  • DEVELOP evaluation criteria for prurigo nodularis (PN) that incorporates characteristic features, including symptoms, presentation, and comorbidities
  • DEVISE a treatment plan that encourages long-term adherence



Chesahna Kindred, MD, MBA, FAAD

Assistant Professor of Dermatology
Howard University College of Medicine
Washington, DC
Kindred Hair & Skin Center
Columbia, MD

Shawn Kwatra, MD, FAAD

Associate Professor of Dermatology and Oncology
Director, Johns Hopkins Itch Center
Johns Hopkins University School of Medicine
Baltimore, MD

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Spire Learning, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation

Global Education Group designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

This educational activity for 0.25 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacist Accreditation Statement

Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education..


Credit Designation Statement

Global Education Group designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-21-162-H01-P) This is a knowledge-based activity.

Disclosures of Conflicts of Interest

Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.

All relevant financial relationships have been mitigated.

Chesahna Kindred, MD, MBA, FAAD (Chair)
  • Consulting Fees (eg, Advisory Board): Aerolase; Eli Lilly and Company; Sun Pharmaceuticals; UCB, Inc.
  • Speakers’ Bureau: Aerolase; Eli Lilly and Company; Novartis Pharmaceuticals Corporation; Nutrafol; Sun Pharmaceuticals; UCB, Inc.
Shawn Kwatra, MD, FAAD
  • Consulting Fees (eg, Advisory Board): AbbVie Inc; Celldex Therapeutics; Galderma; Incyte Corp; Kiniksa Pharmaceuticals; Novartis Pharmaceuticals Corp; Pfizer Inc; Regeneron Pharmaceuticals; Sanofi
  • Contracted Research: Galderma; Kiniksa Pharmaceuticals; Pfizer Inc; Sanofi

Educational Planning Committee

Global Education Group
Rhys Williams, MSN, FNP-C, RN; Lindsay Borvansky; Andrea Funk; Liddy Knight; Ashley Cann; No relevant financial relationships with any commercial interests.

Spire Learning
Andrew Kim, Kimberly Miniter, and Mary Simmons have nothing to disclose.

Lindsay Borvansky: No relevant financial relationships with any commercial interests.

Instructions for Participation and Credit

There is no fee for this educational activity. To receive credit for your participation in this educational activity:

  • Read the objectives and other introductory CME information.
  • Complete the preassessment prior to the start of the activity.
  • Participate in the prurigo nodularis case activity.
  • Complete the postassessment with a passing score of 70% and complete the evaluation at the conclusion of the activity

If you are seeking credit, you must complete the evaluation at the conclusion of the activity.

For information about the accreditation of this program, please contact Global at 303-395-1782 or

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Off-Label Statement

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Spire Learning do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Privacy Policy

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Spire Learning, LLC, is committed to protecting the privacy of personal information from our participants and educational collaborators. Spire maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of personal information.

Collection and Use of Your Personal Information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected and retained, and used by Spire Learning, LLC, to continuously improve the learning experience.

Spire Learning, LLC, will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Spire will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws.

Copyright Information

Copyright © 2022 by Spire Learning, LLC and Global Education Group. All rights reserved including translation into other languages. No part of this publication or activity may be reproduced or transmitted in any form, by any means, without prior written permission of Spire Learning, LLC.