The Role of the Oncology Nurse in the Diagnosis and Treatment of Castleman Disease

Released On
November 30, 2021

Expires On
November 30, 2022

Media Type

Completion Time
60 minutes



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This activity is jointly provided by Global Education and Group Paradigm Medical Communications, LLC.

In collaboration with the Castleman Disease Collaborative Network.

This activity is supported by an educational grant from EUSA Pharma (US) LLC.

Credit Available

  • Nurse Continuing Education — 1.0 contact hour of continuing education
  • Nurse Practitioner Continuing Education — 1.0 contact hour of continuing education
  • PA Continuing Education — maximum of 1.00 AAPA Category 1 CME credit

All other healthcare professionals completing this course will be issued a statement of participation.

Target Audience

This activity has been designed to address the educational needs of oncology nurses, including advanced practice nurses (APNs) and registered nurses (RNs). It will also benefit PAs and other clinicians who manage patients with Castleman disease.

Program Overview

Castleman disease (CD) is a rare group of heterogeneous lymphoproliferative disorders, many of which have an unknown underlying etiology. Owing to its rarity and unknown etiology, many oncology nurses are unaware of this disease, despite it often being managed by hematology/oncology clinics. As a result, this webinar aims to educate oncology nurses on CD so they, in turn, are equipped to educate, advocate for, and support patients through the diagnosis and treatment process.

Learning Objectives

After completing this activity, the participant should be better able to:

  • Outline the signs and symptoms of CD as they relate to early diagnosis
  • Describe US Food and Drug Administration-approved and guideline-recommended therapies for CD



David C. Fajgenbaum, MD, MBA, MSc

Assistant Professor of Medicine
Division of Translational Medicine and Human Genetics
Associate Director, Patient Impact
Penn Orphan Disease Center
Founding Director
Center for Cytokine Storm Treatment and Laboratory
University of Pennsylvania
Co-Founder and Executive Director
Castleman Disease Collaborative Network
Philadelphia, PA

Sudipto Mukherjee, MD, PhD, MPH

Director of Rare Cancers and Blood Diseases
Department of Hematology and Medical Oncology
Leukemia Program
Taussig Cancer Institute
Cleveland Clinic
Cleveland, OH

Gretchen A. McNally, PhD, ANP-BC, AOCNP

Nurse Practitioner—Hematology
The Ohio State University
Arthur G. James Cancer Hospital
Columbus, OH

Accreditation Statement

Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.

This educational activity for 1 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education

This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global Education Group and (name of other entity). Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 1.0 contact hour(s) (which includes 0.2 hour(s) of pharmacology).

Physician Assistants
This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 CME credits. Approval is valid from 11/30/2021 to 11/30/2022. PAs should only claim credit commensurate with the extent of their participation. AAPA reference number: CME-204142.


Term of Offering
This activity was released on November 30, 2021 and is valid for one year. Requests for credit must be made no later than November 30, 2022.

Disclosures of Conflicts of Interest

Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.

All relevant financial relationships have been mitigated.

The faculty have the following relevant financial relationships with ineligible companies:

Name of Faculty or Presenter Reported Financial Relationship
David Fajgenbaum, MD, MBA, MSc Grant Research Support: EUSA Pharma
Sudipto Mukherjee, MD, PhD, MPH Consultant/Independent Contractor: Biophram
International; Bristol-Myers Squibb Company; Celgene
Corporation; Novartis

Grant Research Support: Bristol-Myers Squibb Company;
Jazz Pharmaceuticals, Inc; Novartis

Honoraria: Bristol-Myers Squibb Company; Novartis

Speakers Bureau: EUSA Pharma; Novartis

Other: Abbvie Inc; Blueprint Medicines Corporation; Bristol-
Myers Squibb Company; Celgene Corporation; EUSA
Pharma; Genentech, Inc.; Novartis
Gretchen A. McNally, PhD, ANP-BC, AOCNP Nothing to disclose


The planners and managers have the following relevant financial relationships with ineligible companies:

Name of Planner or Manager Reported Financial Relationship
Rhys Williams, MSN, FNP-C, RN Nothing to disclose
Kristin Delisi, NP Nothing to disclose
Lindsay Borvansky Nothing to disclose
Andrea Funk Nothing to disclose
Liddy Knight Nothing to disclose
Ashley Cann Nothing to disclose
Kim Rodriguez Nothing to disclose
Paradigm Medical Communications, LLC staff members Nothing to disclose


Instructions for Participation and Credit

In order to receive credit for this activity, the participant must:

  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment
  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.


Global Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or

There is no fee required for participation in this activity.

Course Viewing Requirements

Hardware/Software Requirements
This certified CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.

Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+

PDF documents
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Technical Support: If you have any technical problems or playback issues email us at

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Paradigm Medical Communications, LLC do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

If included, signed statements of informed consent granting permission for publication have been obtained for all photographs and videos in which an individual can be identified.


As an ACCME-accredited provider, Paradigm Medical Communications, LLC’s activities must include a balanced view of therapeutic options. Use of generic names contributes to this impartiality. The use of trade names should not be viewed as an endorsement of specific products by Paradigm Medical Communications, LLC.

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Paradigm Medical Communications, LLC or hosted contracted partner is committed to protecting the privacy of those who participate in the activities located at (herein referred to as “website”). The information below describes the security of the website for safeguarding personal information and the rationale for collection and use of personal information.

Security/safeguarding personal information

This website has physical and procedural safeguards in place to prevent unauthorized access to personal information used to access this website.


Collection and use of your personal information

The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CME activity. All evaluative information submitted is collected and retained, and used by Paradigm Medical Communications, LLC to continuously improve the learning experience.

Paradigm Medical Communications, LLC does not transfer, sell, or share personal information with outside parties. Paradigm Medical Communications, LLC will not otherwise disclose personal information unless required to in a legal process. Paradigm Medical Communications, LLC staff members review individual test results to the extent necessary to record and track participants’ credits.


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Contact Information

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