Novel Strategies for Improving Outcomes in Children with Uncontrolled Moderate-to-Severe Asthma – Patient Simulations

Released On
December 14, 2021

Expires On
December 13, 2022

Media Type

Completion Time
90 minutes

Allergy & Immunology, Pediatrics, Pharmacy, Primary Care

Asthma, Pediatrics

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This activity is provided by Horizon CME.

This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme.

Credit Available

  • Physicians — maximum of 1.5 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

This activity is designed to meet the educational needs of allergists, immunologists, pediatric pulmonologists, respiratory clinicians, primary care/internal medicine clinicians, and other healthcare professionals who manage pediatric patients with asthma.

Program Overview

Asthma is one of the most common chronic conditions in the pediatric population, and although existing medications can reduce symptoms, management is still suboptimal. The availability of novel biologic therapies for the treatment of asthma requires clinicians to better understand when and in which patients to consider them.

In the second of a 2-part series, this activity consists of three (3) AliveSimTM patient simulation case scenarios which will address disease severity and treatment selection in patients with uncontrolled moderate-to-severe asthma. Clinicians will learn through the cases about the inflammatory markers associated with moderate-to-severe asthma, how to individualize and select optimal treatment, and communicate effectively with patients and caregivers about the management of moderate-to-severe asthma.

Each scenario will immerse clinicians in “virtual practice sessions” utilizing the AliveSimTM Virtual Practice and Coaching platform, where participants safely practice applying new clinical concepts in asthma. Participants will feel like they’re “in it”, immersed in a series of real-life clinical situations of these patients with asthma. They will interact with virtual peers, make decisions, and receive expert coaching to recognize optimal decision strategies in each scenario.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Assess their competency as they receive expert feedback on decisions
  • Recognize patterns of optimal decision-making used by clinical experts
  • Gain confidence applying new knowledge in diverse situations
  • Increase their comfort level in incorporating changes to their clinical practice




Jonathan Corren MD

Associate Clinical Professor of Medicine and Pediatrics
David Geffen School of Medicine at UCLA
Los Angeles, CA


Lawrence D. Sher MD

Peninsula Research Associates
Medical Director
Rolling Hills East, CA


Accreditation Statement

Horizon CME is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Horizon CME designates this enduring material for a maximum of 1.50 AMA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.

Disclosures of Conflicts of Interest


Dr. Jonathan Corren has served as a Clinical Research Consultant, on an Advisory Board and a Speakers Bureau for AstraZeneca, Genentech, and Sanofi during the past 12 months.*

Dr. Lawrence Sher has received research funding from Regeneron/Sanofi during the past 12 months.*

*Horizon CME has mitigated and resolved all relevant financial relationships.


Those involved in the planning of this activity disclosed no relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients during the past 12 months.

Other Contributors

All other non-faculty contributors and others involved in the planning, development and editing/review of the content disclosed no relevant financial relationships with any entity producing, marketing, re-selling or distributing health care goods or services consumed by or used on patients during the past 12 months.

Instructions for Participation and Credit

There are no fees for participating and receiving CME credit for this enduring activity.

  • To receive CME credit participants must all activity information, including the pre-test, learning objectives, faculty disclosure information, simulation scenario(s) and post-activity evaluation.
  • To view the first simulation scenario, launch the simulation from the link provided using a PC, Mac, Tablet, or Phone with a 4G or higher internet connection.
  • Interact appropriately to satisfy each objective to unlock the next objective and view the next simulation scenario.
  • The simulation will track your progress until all scenario objectives are complete.
  • Exit the simulation at any time, and your progress will be saved so you can return to finish at a later time.
  • As you complete each scenario (1 minimum, 3 total), you will qualify for increasing levels of CE credit (ranging from 0.5 to 1.5 credits). Click or tap "Credit" to determine your CE credit status.
  • Upon successful completion of the evaluation, you can download/print a certificate of credit immediately via the browser.


Course Viewing Requirements

Any modern phone or tablet with at least 2GB of RAM (typically 3-4 years old or newer), or a PC/Mac that is 5 years old or newer. A good user experience requires a broadband connection of 4G or better via a modern web browser (Chrome, Firefox, Safari, or Edge; Internet Explorer is not supported).

Copyright Statement

This CME simulation activity is licensed to Horizon CME. Copyright © 2021 Syandus Inc and Horizon CME. All rights reserved. No part of this simulation activity may be reproduced without written permission from Horizon CME and Syandus Inc.

Disclosure of Unlabeled Use

Horizon CME requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.


This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

Contact Information

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