Nontuberculous Mycobacterial Lung Disease:
Real-World Application of New Guidelines and Treatment Advances

Released On
May 21, 2021

Expires On
May 20, 2022

Media Type

Completion Time
120 minutes

Critical Care, Emergency Medicine, Genetics, Infectious Disease, Pulmonology

Respiratory, Lung Disease

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This activity is provided by Annenberg Center for Health Sciences at Eisenhower.


This educational activity is supported by an educational grant from Insmed.

Credit Available

  • Physicians — maximum of 2.0 AMA PRA Category 1 Credit(s)

All other healthcare professionals completing this course will be issued a statement of participation.

Target Audience

This activity was developed for pulmonologists, infectious disease specialists, and other healthcare professionals who care for patients with lung diseases.

Program Overview

Nontuberculosis mycobacterial lung disease (NTM-LD) is a frequently fatal lung disease that is now more common than tuberculosis in the United States. Treatment is generally very challenging due to lack of medications approved for first-line therapy, adverse events, drug-drug interactions, need for long-term dual and triple combination therapy, among other issues. This is a 2-part activity. Throughout the activity, the faculty share their experiences and provide pearls and pitfalls in overcoming the challenges in managing patients with NTM-LD.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Describe key treatment concepts as described in the 2020 clinical practice guideline on nontuberculous mycobacterial lung disease (NTM-LD) jointly sponsored by American Thoracic Society, European Respiratory Society, European Society of Clinical Microbiology and Infectious Diseases, and Infectious Diseases Society of America
  • Summarize the clinical impact of the latest clinical data and therapeutic advances in NTM-LD
  • Develop patient-centered treatment strategies for NTM-LD that align with the latest evidence-based guideline recommendations and therapeutic advances
  • Collaborate with patients to better individualize treatment over the course of the disease



Shannon Kasperbauer, MD

Associate Professor of Medicine
Division of Mycobacterial and Respiratory Infections
National Jewish Health
University of Colorado Denver
Denver, Colorado


Kevin Winthrop, MD, MPH

Professor of Infectious Diseases, Ophthalmology
Professor of Public Health and Preventive Medicine
Oregon Health & Science University
Portland, Oregon

Physician Accreditation Statement

The Annenberg Center for Health Sciences at Eisenhower is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physician Credit Designation

The Annenberg Center for Health Sciences at Eisenhower designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

It is the policy of the Annenberg Center for Health Sciences to ensure fair balance, independence, objectivity, and scientific rigor in all programming. All faculty and planners participating in sponsored programs are expected to identify and reference off-label product use and disclose any relationship with those supporting the activity or any others with products or services available within the scope of the topic being discussed in the educational presentation.

The Annenberg Center for Health Sciences assesses conflict of interest with its instructors, planners, managers, and other individuals who are in a position to control the content of CE/CME activities. All relevant conflicts of interest that are identified are thoroughly vetted by the Annenberg Center for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. The Annenberg Center is committed to providing its learners with high-quality CE/CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

In accordance with the Accreditation Council for Continuing Medical Education Standards, parallel documents from other accrediting bodies, and Annenberg Center for Health Sciences policy, the following disclosures have been made:

Additional content planners
The following have no significant relationship to disclose:
Chris Fischer, MSc (medical writer)

Annenberg Center for Health Sciences
Staff at the Annenberg Center for Health Sciences at Eisenhower have no relevant commercial relationships to disclose.

Instructions for Participation and Credit

There are no fees for participating and receiving CME credit for this enduring activity. To receive CME credit participants must:

  1. Read the CME/CE information and faculty disclosures.
  2. Participate in the online activity.
  3. Submit the evaluation form.
Certificates will be emailed to the participant

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

The faculty for this activity has disclosed that there will be no discussion about the use of products for non-FDA approved applications.


The ideas and opinions presented in this educational activity are those of the faculty and do not necessarily reflect the views of the Annenberg Center and/or its agents. As in all educational activities, we encourage practitioners to use their own judgment in treating and addressing the needs of each individual patient, taking into account that patient’s unique clinical situation. The Annenberg Center disclaims all liability and cannot be held responsible for any problems that may arise from participating in this activity or following treatment recommendations presented.

Contact Information

For help or questions about this activity please contact Continuing Education:
Annenberg Center for Health Sciences
39000 Bob Hope Drive
Dinah Shore Building
Rancho Mirage, CA 92270
Phone 760-773-4500
Fax 760-773-4513
8 AM – 5 PM, Pacific Time, Monday – Friday