Applying Enhanced Understanding of the Mechanisms of Disease in Generalized Myasthenia Gravis (gMG): Improved Diagnostics and Targeted Treatment Options

Released On
March 9, 2021

Expires On
March 9, 2022

Media Type

Completion Time
60 minutes


Myasthenia Gravis

Scroll to the Bottom of this Information to Begin this Course

Jointly provided by Postgraduate Institute for Medicine and PlatformQ Health Education, LLC in collaboration with the National Organization for Rare Disorders (NORD), Myasthenia Gravis Foundation of America (MGFA), and the Muscular Dystrophy Association (MDA).

Supported by an educational grant from argenx.

Credit Available

  • Physicians — maximum of 1.0 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

The intended audience for this activity program are neuromuscular, neuroimmunology, neuro-ophthalmology, and neurology specialists, along with neurology advanced-practice providers.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Describe the role of pathogenic antibodies in driving the pathophysiology of gMG, their contributions as biomarkers of disease and potential response to therapy, and the need for autoantibody testing
  • Describe the burden of gMG disease and the challenges faced by patients who receive traditional treatments
  • Describe the MOA, efficacy, safety, and place in therapy of emerging biologic treatments for gMG
  • Summarize the correlation between autoantibody status, prediction of therapeutic response, and symptom improvement based on patient-outcome measures


James F, Howard Jr., MD

Professor of Neuromuscular Disease
Professor of Neurology & Medicine
The University of North Carolina
Chapel Hill, NC

Nicholas J. Silvestri MD, FAAN

Associate Professor of Neurology
University at Buffalo Jacobs School of Medicine & Biomedical Sciences
Buffalo, NY

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and PlatformQ Health Education, LLC. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


Credit Designation

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

James F, Howard Jr., MD

  • Consulting Fees: Argenx BVBA, Alexion Pharm, Ra Pharma (now UCB), Immunovant, Viela Bio
  • Other: Research Support to my institution: Alexion Pharm, Argenx, BVBA, Pharma (now UCB)

Nicholas J. Silvestri MD, FAAN

  • Consulting Fees: Alexion, Argenx, Biogen, Immunovant, Sarepta, Strongbridge, UCB

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Carole Drexel, Medical Director PlatformQ Health Education, LLC: Nothing to Disclose.

The PIM planners and managers have nothing to disclose.

The following PlatformQ Health Education, LLC planner, Bridget Griffin, hereby states that she or her spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Method of Participation

There are no fees to participate in this activity. To participate in the activity, go to To receive credit, participants must (1) read the target audience, learning objectives, and disclosure statements, (2) complete the educational activity online, and (3) complete the post-test and activity evaluation. To receive AMA PRA Category 1 Credits™ participants must receive a minimum score of 70% on the post-test.

Hardware/Software Requirements

Participants will need a computer with a recent version of Adobe Flash installed, as well as an internet connection sufficient for streaming media.

Contact Information

Accreditation Support:
Please contact the Postgraduate Institute for Medicine at

Technical Support:
For any technical issues or issues with your CME Certificate, please contact at 1-877-394-1306 or at or at

PlatformQ Health Privacy Policy:

By clicking “Start Activity” you are agreeing to PlatformQ Health’s privacy policy. PlatformQ Health takes your privacy very seriously. The full Privacy Policy found here describes (i) the types of information we collect from you when you visit our Site; (ii) how we use the information we collect; (iii) with whom and why we share it; and (iv) the choices we offer regarding our use of the information. We also describe how to contact us about our privacy practices.

Information we collect is primarily used to communicate with program participants, award CME/CE credits, manage user accounts, recommend relevant programs and perform data analysis to inform educational outcomes.

In plain English, here is what we affirm:

  • You can change your registration profile at any time from our “Profile” page
  • To request any of these changes without logging in, please call us at 1 (877) 394-1306 or email us at
  • You can end your association with PlatformQ Health at any time
  • PlatformQ Health does not spam, nor we do we rent or sell our email list in whole or in part. Any program-related data sharing is for engagement verification and opt-in based further education
  • EU citizens can request a complete record of their account and/or request to have their personal data expunged by contacting with the subject line “Data Request”

You acknowledge and agree that by beginning this activity, you have affirmatively agreed to this Privacy Policy and consented to receiving electronic messages in conformance with this Privacy Policy. Please read the full privacy policy located at: