Managing Immune-Related Adverse Events in the ED With the Advent of Combination Therapies

Released On
October 27, 2020

Expires On
October 27, 2021

Media Type
Internet

Completion Time
60 minutes

Specialty
Hematology-Oncology, Primary Care

Topic(s)
Bone Cancer, Brain Cancer, Breast Cancer, Colon Cancer, Leukemia, Lung Cancer, Lymphoma, Multiple Myeloma, Oncology, Skin Cancer

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This activity is provided by Paradigm Medical Communications, LLC.

This activity is supported by educational grants from Bristol-Myers Squibb and Merck & Co., Inc.

This enduring satellite symposium is not part of the official ACEP20 UNCONVENTIONAL educational program as planned by ACEP’s Educational Meetings Committee

Credit Available

  • Physicians, Physician's Assistants, Nurse Practitioners — maximum of 1.0 AMA PRA Category 1 Credit(s)
  • Emergency Physicians — Approved by the American College of Emergency Physicians for 1.0 hour(s) of ACEP Category I credit

All other healthcare professionals completing this course will be issued a statement of participation.

Target Audience

This activity is designed to meet the educational needs of emergency medicine (EM) clinicians. It may also benefit other members of the multidisciplinary team caring for patients receiving immuno-oncology agents.

Program Overview

As use of immune checkpoint inhibitors (ICI) for various cancers increases, the number of patients presenting to the emergency department (ED) with associated immune-related adverse events (irAEs) will increase as well. This 1.0-hour, CME-certified program, presented by Drs. Christopher J. Coyne and Jayne Viets-Upchurch, will review the fundamentals of ICIs as used for cancer treatment, including standard-of-care regimens and the mechanisms of action for these agents. It will also highlight guideline-recommended approaches to recognizing and treating irAEs associated with ICI monotherapies or combination regimens in the ED setting.

Learning Objectives

Upon proper completion of this activity, participants should be better able to:

  • Review the fundamentals of immune checkpoint inhibition, including standard-of-care regimens and their MOAs
  • Apply guideline-recommended approaches to recognizing and treating irAEs associated with immune checkpoint inhibition monotherapies or combination regimens in the ED setting

Faculty

Christopher J. Coyne, MD, MPH

Christopher J. Coyne, MD, MPH

Assistant Clinical Professor
Emergency Medicine
Radiation Medicine and Applied Science
UC San Diego Health
San Diego, CA

Jayne Viets-Upchurch, MD

Jayne Viets-Upchurch, MD

Assistant Professor
Department of Emergency Medicine
Division of Internal Medicine
The University of Texas MD Anderson Cancer Center
Houston, TX

Accreditation Statement

Physician Accreditation Statement

Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

ACEP Category 1 Credit Statement

Approved by the American College of Emergency Physicians for 1.0 hour(s) of ACEP Category I credit.

Credit Designation

Physician Credit Designation Statement

Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

PA Continuing Education

PAs may claim a maximum of 1.0 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME or a recognized state medical society.

Nurse Practitioner Continuing Education

The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.

Disclosures of Conflicts of Interest

In accordance with ACCME requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below. Any potential conflicts of interest have been resolved.

Christopher J. Coyne, MD, MPH

  • Has no financial relationships to disclose

Jayne Viets-Upchurch, MD

  • Has no financial relationships to disclose

Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Independent peer reviewer:
Marwan Fakih, MD has the following relationships to disclose:

  • Consulting Fees: Amgen Inc; Array Biopharma; Bayer Corporation; Pfizer Inc
  • Speakers Bureau: Amgen Inc; Guardant 360

Resident reviewer:
Meghan Thomas has no financial relationships to disclose.

Resolution of Conflict of Interest

Paradigm Medical Communications, LLC has implemented a system to resolve conflicts of interest for each CME activity to help ensure content is objective, fair and balanced, independent, and aligned with the public interest. Conflicts, if any, are resolved through one or more processes. All CME content in this activity was independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ACCME’s Standards for Commercial Support of Continuing Medical Education.

Instructions for Participation and Credit

To receive a CME certificate of participation, you should:

  • Follow the "Start Activity" button to go to the Paradigm Medical Communications website
  • Follow instructions to register or log in with your professional information
  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation. Your certificate will be saved on the Paradigm Medical Communications website and will not be available in your myCME CME History.

There is no fee required for participation in this activity.

Course Viewing Requirements

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Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.

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This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. Reasonable efforts have been taken to present educational subject matter in a balanced, unbiased fashion, and in compliance with regulatory requirements. However, each activity participant must always use his or her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

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The materials provided for this activity are for informational purposes only, and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC. Paradigm Medical Communications, LLC, accepts no liability for the content referenced in this activity.

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Collection and use of your personal information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CME activity. All evaluative information submitted is collected and retained, and used by Paradigm Medical Communications, LLC to continuously improve the learning experience.

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Contact Information

For questions regarding CME credit, contact the Paradigm CME Department at (845) 398-5949.