Advances in the Treatment Options for dMMR/MSI-H Metastatic Colorectal Cancer with Immunotherapy

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This activity is jointly provided by CancerNet, LLC and Amedco, LLC.

Supported by an independent educational grant from Merck Sharp & Dohme Corp.

Credit Available

• Physicians — maximum of 1.25 AMA PRA Category 1 Credit(s)™
• Nurses — 1.25 Contact Hours

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

This activity is designed to meet the educational needs of medical oncologists, radiation oncologists, surgeons, gastroenterologists, physician assistants, nurse practitioners, nurses, and other healthcare professionals involved in the treatment of colorectal cancer patients.

Program Overview

This activity will cover topics on the diagnosis, treatment, and management of patients with colorectal cancer.

Learning Objectives

Upon completion of this activity, participants should be better able to:

• Assess the results of dMMR/MSI-H testing to determine appropriate patient selection of colorectal cancer (CRC)
• Formulate treatment plans for metastatic CRC using immune checkpoint inhibition, alone or in combination with other therapies
• Apply evidence-based strategies to monitor, recognize and effectively manage potential adverse events associated with immune checkpoint inhibition

Faculty

Accreditation Statement

Physicians/Nurses

In support of improving patient care, this activity has been planned and implemented by Amedco LLC and CancerNet. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

Credit Designation

Credit Designation Statement – Amedco LLC designates this enduring activity for a maximum of 1.25 AMA PRA Category 1 Credits™ for physicians and 1.25 hours for nurses. Learners should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

The following table of disclosure information is provided to learners and contains the relevant financial relationships that each individual in a position to control the content disclosed to Amedco. All of these relationships were treated as a conflict of interest and have been resolved (C7 SCS 6.1-6.2, 6.5). All individuals in a position to control the content of CE are listed below.

All individuals in a position to control the content of CE are listed on the website. If their name is not listed below, they disclosed that they had no financial relationships with a commercial interest.

Axel Grothey, MD

• Has no relevant financial relationships to disclose.

Axel Michael A. Morse, MD, FACP, MHS

• Consulting/advisory committee: Genentech/Roche, Eisai, Inc., Taiho, Ipsen, Lixicon
• Research Funding: Bristol-Myers Squibb, Merck, AstraZeneca

Planners and Managers Disclosures

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME webcast:

• Kamatham A. Naidu, PhD (CancerNet, LLC), has no relevant financial relationships.
• Brian Waggoner (CancerNet, LLC) has no relevant financial relationships to disclose.
• Sheryl Morgan (Amedco) has no relevant financial relationships to disclose.

Instructions for Participation and Credit

There are no fees for participating and receiving CME credit for this enduring activity. To receive CME credit participants must:

1. Read the CME/CE information and faculty disclosures.
2. Participate in the online activity.
3. Submit the evaluation form.

Certificates will be emailed to the participant

Course Viewing Requirements

Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above

Disclosure of Unlabeled Use

Amedco and CancerNet require that faculty participating in any CME/CE activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

Disclaimer

Amedco makes every effort to develop CME/CE activities that are scientifically based.

This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME/CE questions, please contact: Amedco at: certificate@amedcoemail.com

For questions regarding content, please contact: CancerNet at brianw@cancernetus.com.