Optimizing Use of Botulinum Toxin Type A for Pediatric Upper Limb Spasticity: Transforming Science Into Clinical Success

Released On
August 31, 2020

Expires On
August 31, 2021

Media Type

Completion Time
1.0 hour

Neurology, Pediatrics, Physiatry


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This activity is provided by Paradigm Medical Communications, LLC.


This activity is supported by an educational grant from Allergan, Inc.

Credit Available

  • Physicians — maximum of 1.0 AMA PRA Category 1 Credit

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

This activity has been designed to address the educational needs of neurologists, physical medicine and rehabilitation physicians (also known as physiatrists), developmental pediatricians, and orthopedic surgeons. It may also be of benefit to other healthcare providers who are involved in the management of spasticity, including pediatric nurse practitioners and PAs.

Statement of Need/Program Overview

This interactive enduring activity will cover the management of pediatric patients with upper limb spasticity (ULS).

Learning Objectives

Upon proper completion of this activity, participants should be better able to:

  • Evaluate available BoNT-As, including their mechanisms of action, indications, and preparation, as well as their dosing, efficacy, and safety, in pediatric ULS.
  • Identify the anatomy and pathophysiology of musculature associated with pediatric ULS in which BoNT-As have proven effective in reducing symptoms.
  • Describe current methods for ensuring accurate delivery of BoNT-As to the appropriate target muscles for pediatric ULS.


Katharine Alter, MD

Prince George's Hospital Center
Cheverly, MD

Jahannaz Dastgir, DO

Pediatric Neuromuscular Medicine Program
Division of Child Neurology
Goryeb Children’s Hospital
Morristown, NJ

Sherry A. Downie, PhD

Albert Einstein College of Medicine
Bronx, NYN

Accreditation Statement

Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

Katharine Alter, MD

  • Royalty: Demos Media Publishing

Jahannaz Dastgir, DO

  • No financial relationships to disclose.

Sherry A. Downie, PhD

  • Consulting Fees: Allergan, Inc.
  • Speakers Bureau: Allergan, Inc.

Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Independent peer reviewer, Stephen Nichols, MD, has the following financial relationships to disclose:

  • Grant/Research Support: Ipsen Biopharmaceuticals, Inc.

Instructions for Participation and Credit

To receive a CME certificate of participation, you should:
  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment.
  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation.

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

For questions regarding CME credit, contact the Paradigm CME Department at (845) 398-5949.

There is no fee required for participation in this activity.

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This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.


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