Outcomes Trials of Antidiabetic Medications

Released On
October 22, 2018

Expires On
April 22, 2020

Media Type

Completion Time
60 minutes



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Presented by Joslin Diabetes Center in Joint Providership and PlatformQ Health Education, LLC.


This activity is supported by independent educational grants from AstraZeneca, Boehringer Ingelheim Pharmaceuticals, Inc. and Lilly USA, LLC.

Credit Available

  • Physicians — maximum of 1.0 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Joslin Diabetes Center and PlatformQ Health Education, LLC. Joslin Diabetes Center is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statements

Enduring Material

Joslin Diabetes Center designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Date of Release/Expiration

Enduring Material
The enduring material will be available from October 22, 2019 – April 22, 2020.

Learning Objectives

At the conclusion of this activity, participants should be able to:

Outcomes Trials of Antidiabetic Medications

  • Describe the rationale for evaluating the cardiovascular impact of antidiabetes medications, and key data from recent cardiovascular outcomes trials of antidiabetes medications
  • Describe how specific characteristics and components of cardiovascular and renal outcome trial study designs impact the interpretation of the results, and subsequently, the clinical implications of these results
  • Identify evidence from outcomes trials of antidiabetes medications demonstrating non-glycemic benefits that has impacted usage indications and guideline-driven glycemic control programs for people with type 2 diabetes

Intended Audience

Primary: Primary care clinicians (physicians, physician assistants, and nurse practitioners). Secondary: Care support staff such as nurses, certified diabetes educators and pharmacists, diabetes specialists (such as endocrinologists and diabetologists), and specialty clinicians in non-diabetes fields, such as cardiologists and nephrologists.

Method of Participation

There are no fees to participate in this activity. To receive credit, participants must (1) read the target audience, learning objectives, and disclosure statements, (2) complete the educational activity online, and (3) complete the posttest and activity evaluation. It is estimated that this module will take approximately 1 hour to complete. To receive AMA PRA Category 1 Credit™, participants must receive a minimum score of 70% on the posttest.

Hardware/Software Requirements

Participants will need a computer with a recent version of Adobe Flash installed, as well as an internet connection sufficient for streaming media.

Faculty Disclosures

As part of its accreditation with the Accreditation Council for Continuing Medical Education, Joslin Diabetes Center must disclose to the audience of a Joslin continuing medical education activity the existence of any relevant financial relationships between Joslin and/or its planning and/or CME advisory committee members, speakers, and their spouses/partners and commercial entities. Joslin and its planning and CME advisory committee members and speakers must disclose any relationships they and their spouses/partners have or have had in the prior 12 months with proprietary entities producing healthcare goods or services, with the exception of nonprofit or government organizations and non-healthcare-related companies, which are exempt.

Financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fees, honoraria, ownership interests (e.g., stocks, stock options, or other ownership interest, excluding diversified mutual funds), or other financial benefit in any amount. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected.

If a faculty or planning committee member has no information to disclose, this information will also be provided. If a faculty or planning committee member refuses to disclose, he/she will not be able to participate in the planning, management, presentation, or evaluation of any Joslin Diabetes Center CME activity. In addition, faculty have been asked to disclose when a product or device is not labeled for the use under discussion. The opinions and comments expressed in this program are those of the speakers and should not be considered the opinions or comments of Joslin Diabetes Center.

The planners and faculty have reported the following financial relationships with commercial interests. Via Joslin internal review, any relationship deemed relevant to the content of this activity has been identified and resolved through Joslin’s internal processes.

The faculty and planning committee members for this program have disclosed the following:


  • Dr. Richard S. Beaser*†, Senior Staff Physician and Medical Director of CME, Joslin Diabetes Center, has no relevant financial relationships with regard to this activity.
  • Dr. Om P. Ganda, MD, Medical Director of the Lipid Clinic, Chair of the Clinical Oversight Committee, Joslin Diabetes Center, is content editor for DynaMed Plus, receives grant/research support from Amarin, and has participated in scientific speaker activities with Boehringer-Ingelheim.
  • Dr. Muthiah Vaduganathan, MD, MPH, Cardiologist, Brigham and Women’s Hospital, is a consultant for Amgen, AstraZeneca, Baxter HealthCare, Bayer AG, Boehringer-Ingelheim, and Relypsa.

Planning Committee

  • Elizabeth del Nido, Senior Program Manager, PlatformQ Health Education, has no relevant financial relationships with regard to this activity.
  • Joseph Chebli, PharmD, Medical Director, PlatformQ Health Education, holds stock in Bristol Myers Squibb, Medtronic, and Pfizer.

Joslin CME Advisory Committee

  • Jerry Cavallerano, OD, Optometrist, Beetham Eye Institute, Joslin Diabetes Center, has no relevant financial relationships.
  • Nuha El Sayed, MD, Staff Physician and Medical Director, Professional Education, Joslin Diabetes Center, has no relevant financial relationships.
  • Erin Kelly, M.Ed., RN, BSN, CDE, Adult Diabetes Educator, Joslin Diabetes Center, holds stock in Tandem Diabetes Care.
  • Lyle Mitzner, MD, Staff Physician, Joslin Diabetes Center, is a consultant for Conversa Health.
  • Alissa Segal, Pharm D, CDE, CDTC, FCCP, Clinical Pharmacist, Joslin Diabetes Center, has no relevant financial relationships.
  • Robert C. Stanton, MD, Chief of Nephrology, Joslin Diabetes Center, has no relevant financial relationships
  • Elena Toschi, MD, Staff Physician, Joslin Diabetes Center, has no relevant financial relationships.

* Also on the Planning Committee

† Also on the CME Advisory Committee

Contact Information

Please send content inquiries to: cme@joslin.harvard.edu.

For technical problems with the site or issues with your CME Certificate, please contact DiabetesSeriesLive at 877-394-1306 or at Support@DiabetesSeriesLive.com.

Disclaimers (if applicable):

The material is prepared based on a review of multiple sources of information but is not exhaustive of the subject matter. Therefore, health care professionals and other individuals should review and consider other publications and materials about the subject matter other than relying solely on the information contained in this material.

The information presented at this CME program represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by Joslin Diabetes Center, DiabetesSeriesLive, PlatformQ Health Education, LLC or the program grantor. Reasonable efforts have been made to present educational subject matter in a balanced, unbiased fashion and in compliance with regulatory requirements. Each participant must use his/her personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

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