Podcast III: Evaluate the Role of Currently Available Antifibrotic Agents in the Treatment of IPF and SSc-ILD

Released On
August 26, 2019

Expires On
August 26, 2020

Media Type

Completion Time


Critical Care, Emergency Medicine, Geriatric Medicine, Hospitalist, Pathology, Pharmacy, Pulmonology, Radiology, Rheumatology

Jointly Provided by AKH, Inc. and peerXchange, Inc.

This activity is supported by an independent educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.

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Credit Available

  • Physicians — maximum of 0.5 AMA PRA Category 1 Credit(s)
  • Physician Assistants — NCCPA accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by ACCME.

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

This curriculum is designed to meet the educational needs of pulmonologists, internists, rheumatologists, primary care physicians, nurse practitioners, and physician assistants who provide care to patients with idiopathic pulmonary fibrosis and systemic sclerosis-interstitial lung disease.

Program Overview

The management of progressing fibrotic pulmonary disease continues to evolve and guidelines are challenged to stay abreast of, and to reflect, advances from recent clinical studies or drug approvals. Clinicians need to be aware of this challenging landscape to develop treatment plans that are current and that help patients to achieve optimal outcomes. In this podcast, Drs. Zibrak and Saketkoo will review the evidence supporting the use of antifibrotic agents, specifically nintedanib and pirfenidone in patients with IPF and the emerging evidence that these drugs may be useful in SSc-ILD.

  • What is the role of currently approved antifibrotics in the treatment of PF-ILD?
  • What is the current status of antifibrotics?
  • Which patients with reduced lung function might be considered for treatment with antifibrotic therapy?
  • What is the current thinking with managing side effects associated with antifibrotic therapy?
  • Are there shared perspectives on treatment among rheumatology and pulmonary ILD specialists?

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Evaluate the role of currently available antifibrotic agents in the treatment of patients with pulmonary fibrosis associated with IPF and SSc-ILD.


Joseph D. Zibrak, MD

Associate Professor of Medicine
Harvard Medical School
Director, ILD Center
Division of Pulmonology and Critical Care
Beth Israel Deaconess Medical Center
Boston, MA

Lesley Anne Saketkoo, MD, MPH

Associate Professor of Medicine
Tulane University School of Medicine
Clinical Immunology, Allergy and Rheumatology, Pulmonary Diseases, Critical Care and Environmental Medicine
Director, New Orleans Scleroderma & Sarcoidosis Patient Care & Research Center
Co-Director, UMC Comprehensive Pulmonary Hypertension Center
New Orleans, LA

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AKH Inc., Advancing Knowledge in Healthcare and peerXchange, Inc. AKH Inc., Advancing Knowledge in Healthcare is accredited by the ACCME to provide continuing medical education for physicians.

Physician Assistants: NCCPA accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by ACCME.

Credit Designation

AKH Inc., Advancing Knowledge in Healthcare designates this enduring activity for a maximum of .5 AMA PRA Category 1 Credit(s)™.

Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.

Disclosures of Conflicts of Interest

It is the policy of AKH Inc. and peerXchange, Inc. to ensure independence, balance, objectivity, scientific rigor, and integrity in all of its continuing education activities. The faculty must disclose to the participants any significant relationships with commercial interests whose products or devices may be mentioned in the activity or with the commercial supporter of this continuing education activity. Identified conflicts of interest are resolved by AKH prior to accreditation of the activity and may include any of or combination of the following: attestation to non-commercial content; notification of independent and certified CME expectations; referral to National Faculty Initiative training; restriction of topic area or content; restriction to discussion of science only; amendment of content to eliminate discussion of device or technique; use of other faculty for discussion of recommendations; independent review against criteria ensuring evidence support recommendation; moderator review; and peer review. AKH Inc. planners and reviewers have no relevant financial relationships to disclose.

Joseph D. Zibrak, MD

Dr. Zibrak receives consulting fees from Boehringer Ingelheim, Genentech, and Hoffman LaRoche and participates on the Speakers Bureau for Boehringer Ingelheim and Genentech.

Lesley Anne Saketkoo, MD, MPH

Dr. Saketkoo has nothing to disclose.

Planning Committee

peerXchange Disclosures

Deborah Dean, President: has disclosed no financial relationships.

Wendy Gloffke, PhD: has disclosed no financial relationships.

AKH Staff and Reviewers Disclosures

Dorothy Caputo, MA, BSN, RN, Lead Nurse Planner/Reviewer: has disclosed no financial relationships.

Patricia Brignoni, AKH Director of Operations/Reviewer: has disclosed no financial relationships.

Method of Participation

There are no fees for participating and receiving CME credit for this enduring activity. During the period August 26, 2019 through August 26, 2020, participants must 1) read the CME information, including learning objectives and facul¬ty disclosures; 2) study the educational activity; and 3) complete the pre-test, post-test and evaluation form. To answer the questions, click on your selected choice for each answer then proceed to the next question. Once completed, submit and your post-test will automatically be graded. Once you successfully complete the post-test (score of 70% or greater) and activity evaluation, your Statement of Credit will be made available immediately to view or print for your records.

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Disclosure of Unlabeled Use

This educational activity may include discussion of uses of agents that are investigational and/or unapproved by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


This course is designed solely to provide the healthcare professional with information to assist in his/her practice and professional development and is not to be considered a diagnostic tool to replace professional advice or treatment. The course serves as a general guide to the healthcare professional, and therefore, cannot be considered as giving legal, nursing, medical, or other professional advice in specific cases. AKH Inc. and peerXchange, Inc. specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through participant's misunderstanding of the content.

Copyright Statement

© 2019. This CME activity is held as copyrighted © by peerXchange, Inc. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).

If you have any questions regarding CME or relating to the accreditation of this activity, please contact AKH at tbrignoni@akhcme.com

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