Challenges and Developments in Opioid-induced Constipation

Released On
May 30, 2018

Expires On
May 30, 2019

Media Type

Completion Time
45 minutes



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This activity is provided by Horizon CME.


Supported in part by an independent educational grant from AstraZeneca.

Credit Available

  • Physicians — maximum of 0.75 AMA PRA Category 1 Credit(s)™

All other health care professionals completing this course will be issued a statement of participation.

Target Audience

The target audience for this CME initiative includes oncology nurse practitioners, physician assistants, pharmacists, and nurse specialists working in all phases of oncology care.

Program Overview

This webcast will review the advantages and disadvantages of currently available treatment options for opioid-induced constipation (OIC). Learners will be provided with better tools to formulate evidence-based treatment plans and to encourage patient/provider communication.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Encourage patient communication regarding bowel patterns while on opioid therapies to improve identification, prevention, and monitoring of opioid induced constipation (OIC)
  • Formulate evidence-based treatment plans for the management of OIC in cancer patients
  • Compare the mechanisms and clinical profiles of prescription medications used in the treatment of refractory OIC


Mihir M. Kamdar, MD

Harvard Medical School
Associate Director, Division of Palliative Care
Massachusetts General Hospital
Boston, MA

Content Chair
Nicole Ross, MSN, CRNP, AOCNP
Oncology Nurse Practitioner
Fox Chase Cancer Center
Philadelphia, PA

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the providership of Horizon CME. Horizon CME is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

Horizon CME designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™;. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

Mihir Kamdar, MD: Dr. Kamdar has served on an Advisory Board for Amorsa Therapeutics, and has stock and/or bond holdings with Amorsa Therapeutics.

Nicole Ross, MSN, CRNP, AOCNP: Nicole Ross discloses no relevant financial relationships with any ACCME-defined commercial interests.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Method of Participation

There are no fees to participate in the activity. Participants must review all activity information, including the learning objectives, disclosure statements, and content. To receive credit for participation, participants must complete the post-test (achieving a passing grade) and program evaluation. Certificates can be printed immediately.


Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above.


The information presented in this activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician regarding diagnosis and treatment of a specific patient’s medical condition.

The opinions expressed in this educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Contact Information

Accreditation Support: Contact Horizon CME.