Overcoming Challenges for Children and Adolescents with MS: A Comprehensive Review for Pediatric Clinicians of MS Symptoms, Diagnosis, Treatment, and Coordination of Care

Jointly provided by The Consortium of Multiple Sclerosis Centers (CMSC) and Nurse Practitioner Alternatives (NPA) in collaboration with Catamount Medical Education.

This activity is supported by educational grants from Novartis Pharmaceuticals Corporation, Sanofi Genzyme and Mallinckrodt Pharmaceuticals.

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Release date: December 1, 2017

Valid through: December 1, 2018

Specialty: Neurology

Topic: MS

Media: Internet

Estimated Time to Complete Activity: 90

Target Audience

This activity is for pediatric physicians, PAs, nurse practitioners, and other healthcare professionals in the pediatric setting who are involved in the care of patients with MS.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Review the signs and symptoms of MS to facilitate prompt diagnosis and appropriate triage
  • Identify conditions that mimic MS with strategies to facilitate a differential diagnosis in a pediatric patient
  • Discuss evidence-based management approaches for the pediatric patient and the family
  • Review current and emerging disease modifying therapies appropriate for the treatment of MS in children and adolescents
  • Identify the characteristics of an MS relapse versus progression versus specific variants seen in pediatric patients as normal landmarks in growth and development
  • Review best practices of collaborative care management of pediatric MS patients

Credit Available

  • Physicians — maximum of 1.5 AMA PRA Category 1 Credit(s)
  • Nurses1.5 contact hours

All other healthcare professionals completing this course will be issued a statement of participation.


Tanuja Chitnis, MD, FAAN, Program Chair

Associate Professor of Neurology
Harvard Medical School
Director, Partners Pediatric MS Center
Massachusetts General Hospital
Medical Director, CLIMB Study
Partners MS Center
Scientist, Ann Romney Center for Neurologic Diseases
Brigham and Women’s Hospital

Sona Narula, MD

Assistant Professor of Clinical Neurology
The Children’s Hospital of Philadelphia
University of Pennsylvania

Elizabeth Kunzelman, BSN, RN

Multiple Sclerosis Clinic
The Children’s Hospital of Philadelphia

Physician Continuing Medical Education

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Consortium of Multiple Sclerosis Centers (CMSC) and Nurse Practitioner Alternatives (NPA) in collaboration with Catamount Medical Education.

The Consortium of Multiple Sclerosis Centers is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

The CMSC designates this enduring activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Accreditation Statement

Nurse Practitioner Alternatives (NPA) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Credit Designation

NPA designates this enduring activity for a maximum of 1.5 Continuing Nursing Education Credit(s)

Disclosures Policy

In accordance with the ACCME Standards for Commercial Support, the Consortium of Multiple Sclerosis Centers (CMSC), Nurse Practitioner Alternatives (NPA), and Catamount Medical Education require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. CMSC, NPA, and Catamount Medical Education resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs. Furthermore, CMSC, NPA, and Catamount Medical Education seek to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. CMSC, NPA, and Catamount Medical Education are committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

The following faculty report that they have relevant financial relationships to disclose:

Tanuja Chitnis, MD, FAAN, Program Chair
  • • Consulting Fees: Bayer, Roche-Genentech, and Sanofi Genzyme
  • • Contract Research: EMD Serono, Octave Biosciences, Verily Life Sciences
Sona Narula, MD
  • No relevant financial relationships
Elizabeth Kunzelman, BSN, RN
  • No relevant financial relationships
Activity Staff Disclosures
  • • The planners, reviewers, editors, staff, or other members at CMSC who control content have declared that they have no relevant financial relationships.
  • • Laurie Scudder, DNP, NP, has served as Nurse Planner for this activity. She has declared that she has no relevant financial relationships.
  • • The planners, reviewers, editors, staff, CME committee, or other members at Catamount Medical Education who control content have declared that they have no relevant financial relationships.

Method of Participation/How to Receive Credit

(1) There are no fees for participating in and receiving credit for this activity. (2) Review the activity objectives and CME/CE information. (3) Complete the CME/CE activity. (4) Complete the online posttest. A score of at least 66.67% is required to successfully complete this activity. The participant may take the test until successfully passed. (5) Complete the CME/CE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs. (6) Credit documentation/reporting: If you are requesting AMA PRA Category 1 Credit(s)™, nursing credit(s) or a certificate of participation—your CME/CE certificate will be available for download.

Technical Requirements

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Disclosure of Unlabeled Use

CMSC, NPA, and Catamount Medical Education require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. CMSC, NPA, and Catamount Medical Education do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.


CMSC, NPA, and Catamount Medical Education present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. CMSC, NPA, and Catamount Medical Education, and the commercial supporters assume no liability for the information herein.

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Contact Information

If you have questions about this CME activity, please contact Catamount Medical Education at 860-661-4159 or info@catmeded.com.