Comorbid Conditions and Antipsychotic Use in Patients with Depression

Jointly provided by Global Education Group and Novus Medical Education.

This activity is supported by an independent education grant from Otsuka America Pharmaceutical, Inc and Lundbeck.

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Release date: July 26, 2017

Valid through: July 26, 2018

Specialty: Psychiatrists

Topic: Major Depressive Disorder (MDD)

Media: Internet

Estimated Time to Complete Activity: 30 minutes

Target Audience

This activity is intended for primary care clinicians, psychiatrists and other mental healthcare professionals.

Program Overview

Major Depressive Disorder (MDD) is a debilitating condition that nearly 20% of the general population in the United States will experience at some point in their life. The ultimate goal of care providers is to move patients suffering from MDD to remission, then recovery, and to avoid a relapse. While this alone is a challenge for clinicians, it becomes even more difficult in patients with cardiovascular disease risk factors such as smoking, diabetes, hypertension, obesity and dyslipidemia. Further complicating matters are the risks associated with some medications used to treat depression.

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • Describe the association between cardiovascular disease risk factors and depression
  • Summarize the most recent guidelines for metabolic monitoring
  • Characterize the metabolic risk associated with atypical antipsychotics
  • Identify pharmacologic agents associated with a lower metabolic risk

Credit Available

  • Physicians — maximum of 0.5 AMA PRA Category 1 Credit

All other healthcare professionals completing this course will be issued a statement of participation.


Thomas W. Heinrich, MD

Professor of Psychiatry and Family Medicine
Director, Division of Consultation-Liaison Psychiatry
Medical College of Wisconsin
Milwaukee, WI

J. Sloan Manning, MD

Co-Director, Mood Disorders Clinic
Moses Cone Family Medicine Residency
Adjunct Associate Professor
University of North Carolina at Chapel Hill
Greensboro, NC

Physician Continuing Medical Education

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and FocusCME. Global is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

Global Education Group designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

Global Education Group (Global) requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

  • Dr. Heinrich: Reports no financial conflicts of interest
  • Dr. Manning: Consultant & Speakers’ Bureau — Otsuka, Sunovion, Takeda/Lundbeck

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

  • Andrea Funk: nothing to disclose
  • Steven Scrivner: nothing to disclose

Instructions for Participation and Credit

There are no fees for participating and receiving credit for this activity.

In order to receive credit, participants must: (1) Watch the webcast; (2) Complete the posttest with a passing score of 70% or higher, and (3) Complete the CME evaluation.

Statements of credit will be issued online.

Hardware and Software Requirements

This site is best viewed with an HTML5 compatible browser, this list includes the current versions for Windows: Microsoft Windows 2000 or higher, Flash Player Plugin (v7.0.1.9 or greater), Internet Explorer (v5.5 or greater), or Firefox, Adobe Acrobat Reader*. For Mac: Mac OS 10.2.8 or higher, Flash Player Plugin (v7.0.1.9 or greater), Safari, Adobe Acrobat Reader*, Internet Explorer is not supported on the Macintosh.
*Required to view printable (PDF) version of the lesson.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Novus Medical Education do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Contact Information

For information about the accreditation of this program, please contact Global at 303-395-1782 or