Emerging Immunotherapies for Hematologic Malignancies: Improving Patient Outcomes by Harnessing the Immune System

Small Molecule Immunomodulatory Drugs

Module 2

Jointly provided by The Leukemia & Lymphoma Society, Postgraduate Institute for Medicine and RMEI, LLC.

Funding provided by The Leukemia & Lymphoma Society.

Scroll to the Bottom of this Information to Begin this Course

Release date: March 12, 2015

Valid through: March 12, 2016

Specialty: Hematology, Oncology

Estimated Time to Complete Activity: 45 minutes

Media: Internet

Target Audience

This activity is primarily for researchers in hematology/oncology, and for hematologists and oncologists who diagnose and treat patients with hematologic malignancies; it is also intended for others with an interest in hematologic malignancies. This program is designed to provide the intended audience with the most current and accurate information about therapeutic advances in immunology for treating and improving outcomes for patients with hematologic malignancies.

Learning Objectives

Small Molecule Immunomodulatory Drugs - Module 2

John Gribben, MD, DSc, FRCP, FRCPath, FMedSci

Upon completion of this activity, participants should be better able to:

  1. Explain the mechanisms whereby hematologic cancer cells alter host immune responses
  2. Describe how changes in host immune response to hematologic cancer cells can be prevented or reversed by immunomodulatory drugs including lenolidomide
  3. Discuss host immune responses as targets of novel therapeutic approaches to treat hematologic malignancies

Credit Available

  • Physicians — maximum of 0.75 AMA PRA Category 1 Credit(s)

All other health care professionals completing this course will be issued a statement of participation.

Faculty

John Gribben, MD, DSc, FRCP, FRCPath, FMedSci
Chair of Medical Oncology
Barts Cancer Institute
Barts and the London School of Medicine and Dentistry
Queen Mary University of London
London, UK

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The Leukemia & Lymphoma Society, Postgraduate Institute for Medicine and RMEI, LLC. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures of Conflicts of Interest

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy.  PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

John Gribben, MD, DSc, FRCP, FRCPath, FMedSci
  • Consulting fees: Roche/Genentech, Pharmacyclics, Mundipharma, AbbVie, Celgene, and MorphoSys

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

The following PIM planners and managers, Laura Excell, ND, NP, MS, MA, LPC, NCC, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CCMEP, and Jan Schultz, MSN, RN, CCMEP, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following Leukemia & Lymphoma Society planners and managers, Lee Greenberger, PhD, Yixian Zhang, PhD, Nikay Thomas, and Clare Karten, MS, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following RMEI, LLC planners and managers, Nora Hartley, MLIS and Lillian McVey, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

Instructions for Participation and Credit

There are no fees for participating and receiving credit for this activity. During the accredited period, participants must read the learning objectives and faculty disclosures; study the educational activity; and complete the post-test and the evaluation form. If you pass the post-test and complete the evaluation, your certificate will be available immediately for download in PDF format.

Hardware and Software Requirements

This site is best viewed with an HTML5 compatible browser, this list includes the current versions of Mircrosoft Internet Explorer, Mozilla Firefox, Google Chrome, and Apple's Safari. You can visit the independent (3rd party) site www.whatismybrowser.com to determine if you have the latest version of your browser. Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. That software may be: Adobe Flash, Apple Quicktime, Adobe Acrobat, Microsoft Powerpoint, Windows Media Player, and Real Networks Real One Player. Where such software is required it will be indicated.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. 

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners.  Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.