The Intersection Between Side Effects and Adherence in MS Therapy

Jointly Sponsored/Co-provided by: The University of Texas Southwestern Medical Center, Postgraduate Institute for Medicine, and Medical Logix, LLC.

Supported by Independent Educational Grants from Genzyme, a Sanofi Company and Novartis..

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Release date: December 9, 2013

Valid through: December 9, 2014

Specialty: Neurology

Estimated Time to Complete Activity: 30 minutes

Target Audience

This activity is intended for healthcare professionals, specifically, neurologists, internists, family practice physicians, nurse practitioners, physician assistants, registered nurses and other providers involved in the care of patients with multiple sclerosis.

Statement of Need

The complexity of MS patient management is increasing dramatically, based on the growth of novel disease-modifying therapy options. One of the most challenging issues to face neurologists in the coming years is the integration of these newer therapies into their clinical armamentarium. With the growing complexity of patients and intervention strategies, there exists a need for more intense continuing medical education. These patient centered CME/CNE activities allow MS treating clinicians to learn in the context of actual MS patients. With new disease-modifying therapies available and emerging, there is a unique opportunity to provide educational experiences in the context of real world referrals that can alter long-term practice patterns.

Related Courses

This course is part 1 of 3, learners may also be interested in Case #2 - The Risk/Benefit Analysis of MS Therapies: One Patient's Dilemma and Case #3 - Clinical Decision Making in MS: Evaluating a Patient with Concerns about Symptoms and Therapeutic Efficacy

Learning Objectives

Upon completion of this activity, participants should be better able to:

  • List MS therapies indicated for the treatment of clinically isolated syndrome
  • Describe prognostic factors in assessing relative risk of MS
  • Discuss therapeutic decision making in the context of patient adherence
  • Outline actions that may be taken to address patient adherence to MS therapy
  • Provide appropriate care and counsel for patients and their families

Credit Available

  • Physicians — maximum of 0.5 AMA PRA Category 1 Credit(s)
  • Nurses — 0.5 Contact Hours

All other health care professionals completing this course will be issued a statement of participation. There are no fees or prerequisites.


Benjamin M. Greenberg, MD, MHS
Deputy Director, Multiple Sclerosis Program Director, Transverse Myelitis, Neuromyelitis Optica and Pediatric Demyelinating Disease Program
Cain-Denius Scholar for Mobility Disorders
Department of Neurology and Neurotherapeutics
Department of Pediatrics
UT Southwestern Medical Center
Children's Medical Center
Dallas, Texas

Joseph K. Vaughan, JR., MD
Assistant Professor
Department of Neurology and Neurotherapeutics
UT Southwestern Medical Center
Dallas, Texas

Physician Continuing Medical Education

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of The University of Texas Southwestern Medical Center and Medical Logix LLC. The University of Texas Southwestern Medical Center is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

The University of Texas Southwestern Medical Center designates each enduring material case for a maximum of 0.50 AMA PRA Category 1 Credit(s)TM. Participants should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Accreditation Statement

Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Credit Designation

Each of these educational activities are for 0.5 contact hours, provided by Postgraduate Institute for Medicine.

Disclosures of Conflicts of Interest

Benjamin M. Greenberg, MD, MHS
  • Consultant: Biogen Idec, Chugai, GlaxoSmithKline, Novartis, Sanofi
  • Ownership Interest: Amplimmune, DioGenix
Joseph K. Vaughan, Jr., MD
  • Speaker: Nautilus Neurosciences, Transdermal Therapeutics

The following Postgraduate Institute for Medicine planners and managers, Laura Excell, ND, NP, MS, MA, LPC, NCC, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CCMEP, and Jan Schultz, RN, MSN, CCMEP, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following Medical Logix, LLC planners/managers, John Gentile and Michael Speidel, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following UT Southwestern employee, Anne Perch, hereby states that she or her spouse/life partner does not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.



Format and Method of Participation

There are no fees for participating and receiving CME or CNE credit for this activity. During the accreditation period, participants must read the learning objectives and faculty disclosures and review this internet-based activity. To take the post-test, please click on the post-test button below the slide window of the player. Complete the post-test and evaluation and attest to the amount of time spent in the activity. Upon receiving a score of 70% or above, print your CME or CE certificate.

Hardware and Software Requirements

Processor Speed: 1.4 GHz P3
Memory: 256 MB RAM (20MB available)
Operating Systems Supported: Windows 2000/XP, MAC
Browsers Supported: Internet Explorer 5.5 or greater, Mozilla Firefox and Safari 3.525 or greater
Additional Requirements: Flash player 8.0 or greater, 800x600 Resolution or higher with 32-bit color
Connection Speed: 128 Kbps or better
Adobe Acrobat 6.0 or greater


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Technical Questions

Please click on the Help button within the online player, or email MS-Leaders at

Please note: Starting this program will take you to the website, which will be where your results and certificate will be stored. To view the full programs, you will need to register for in the top right hand corner of the homepage. Registration is free of charge and takes less than a minute.